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Table 6 Association of V89L and G34R polymorphisms with types of hypospadias

From: Genetic and other epidemiological risk factors of infants and children with hypospadias: a case control study

Types of hypospadias

V89L polymorphism

p value

G34R polymorphism

p value

VV (N = 22)

VL + LL (N = 28)

GG (N = 29)

GR + RR (N = 21)

No

%

No

%

No

%

No

%

Glanular

10

45.5

9

32.1

x2 = 2.715

p = 0.607

15

51.7

4

19.0

x2 = 10.849

p = 0.028*

Penoscrotal

3

13.6

6

21.4

4

13.8

5

23.8

Coronal

4

18.2

6

21.4

7

24.1

3

14.3

Sub coronal

4

18.2

3

10.7

1

3.4

6

28.6

Mid-shaft

1

4.5

4

14.3

2

6.9

3

14.3

  1. Bold indicated that p < 0.05 was regarded as a significant value
  2. x2: Chi-square test