Table 3 Association of promoter methylation of APC, RARβ2, RASSF1A, and TIMP3 with urogenital schistosomiasis

APC

Age group

0.433

5–10

13

3(23.1)

11–16

216(28.6)

Sex

0.697

Male

1

4(23.5)

Female

17

5(29.4)

Intensity of infection

0.999

Light

32

9(28.1)

Heavy

2

0(0)

Haematuria

0.277

Yes

11

2(18.2)

No

23

7(30.4)

RARβ2

Age group

0.548

6–10

13

10(76.9)

11–16

21

13(61.9)

Sex

0.666

Male

17

12(70.6)

Female

17

11(64.7)

Intensity of infection

0.999

Light

32

21(25.6)

Heavy

2

2(100)

Haematuria

0.899

Yes

11

7(63.6)

No

23

16(69.6)

RASSF1A

Age group

0.492

6–10

13

4(38.5)

11–16

21

9(47.6)

Sex

0.914

Male

17

7(41.2)

Female

17

6(35.3)

Intensity of Infection

0.999

Light

32

13(40.6)

Heavy

2

0(0)

Haematuria

0.851

Yes

11

4(36.4)

No

23

9(39.1)

TIMP3

Age group

0.235

6–10

13

9(69.2)

11–16

21

9(42.9)

Sex

0.096

Male

17

11(64.7)

Female

17

7(41.2)

Intensity of Infection

0.999

Light

32

18(56.3)

Heavy

2

0(0)

Haematuria

0.385

Yes

11

7(63.3)

No

23

11(47.8)