Variable | Timing | GnRHa (p value) | BTO (p value) | Control (p value) |
---|---|---|---|---|
Mean weight (kg) | Inception | 65.7 ± 9.6 | 67.0 ± 10.7 | 68.6 ± 11.2 |
2nd month | 65.9 ± 9.3 (p 0.41) | 67.8 ± 10.5 (p < 0.001) | 68.6 ± 11.2 (p 0.52) | |
4th month | 67.0 ± 9.8 (p 0.007) | 69.0 ± 10.5 (p < 0.001) | 68.7 ± 11.0 (p 0.48) | |
6th month | 67.8 ± 10.0 (p 0.001) | 70.2 ± 10.7 (p < 0.001) | 68.7 ± 11.0 (p 0.22) | |
Mean BMI (kg/m2) | Inception | 25.2 ± 5.2 | 25.1 ± 3.4 | 25.5 ± 4.6 |
2nd month | 25.2 ± 4.9 (p 0.79) | 25.4 ± 3.4 (p < 0.001) | 25.5 ± 4.6 (p 0.46) | |
4th month | 25.6 ± 5.1 (p 0.004) | 25.9 ± 3.4 (p < 0.001) | 25.5 ± 4.6 (p 0.41) | |
6th month | 26.0 ± 5.2 (p < 0.001) | 26.4 ± 3.5 (p < 0.001) | 25.5 ± 4.6 (p 0.24) | |
Proportion with ECOG score > 1 (%) | Inception | 85.7% | 83.5% | |
2nd month | 72.0% (p 0.001) | 46.2% (p < 0.001) | ||
4th month | 33.3% (p < 0.001) | 34.8% (p < 0.001) | ||
6th month | 25.0% (p < 0.001) | 19.0% (p < 0.001) | ||
Mean tPSA (ng/ml) | Inception | 38.2 ± 23.3 | 47.2 ± 33.0 | |
3rd month | 9.2 ± 6.9 (p < 0.001) | 14.4 ± 19.2 (p < 0.001) | ||
6th month | 5.0 ± 3.4 (p 0.001) | 8.5 ± 16.2 (p < 0.001) |