Comparison of the effect of vaginal vitamin E cream with conjugated estrogen vaginal cream on vulvovaginal atrophy and overactive bladder syndrome: a randomized controlled trial

African Journal of Urology

Table 2 Comparison of mean score of VVA and VHI and OABS between study groups

Variable	Intervention mean (SD)	Control mean (SD)	AMD (95%CI)^a	P
VVA score (before intervention)	10.91 (1.5)	10.52 (1.9)	–	0.348^b
VVA score (after intervention)	3.30 (3.8)	3.91 (3.2)	0.63 (− 1.03–2.28)	0.449^c
VHI score (before intervention)	10.1 (4.5)	9.8 (2.6)	–	0.728^b
VHI score (after intervention)	13.2 (0.28)	13.8 (0.28)	0.64 (− 0.13–1.42)	0.101^c
OABSS (before intervention)	10.3 (3.0)	8.6 (1.9)	–	0.006^b
OABSS (after intervention)	4.701 (0.50)	4.962 (0.55)	0.261 (− 1.278–1.799)	0.736^c

The Acquired range is 0–15 for the VVA score and 5–25 for the VHI score and 0–15 for the OABSS
OABS, overactive bladder syndrome; OABSS, overactive bladder syndrome score; SD, standard deviation; VHI, vaginal health index; VVA, vulvovaginal atrophy
^aAdjusted mean difference (95% confidence interval)
^bIndependent t-test
^cANCOVA test with adjusted the baseline score