Table 2 Relation between p27 immunoreactivity and clinicopathological variables of the studied cases
Item (n.) | P27 immunopositivity | p-value | P27 expression score | p-value | |||||
|---|---|---|---|---|---|---|---|---|---|
Positive n (%) | Negative n (%) | Â | Low score n (%) | High score n (%) | |||||
Mild chronic cystitis (20) | 0 | 12 (100) | 0.01 | 0 | 0 |  < 0.001 | |||
Urothelial carcinoma (60) | 26 (43.3) | 34 (56.7) | Â | 19 (73) | 7 (27) | Â | |||
Age |  < 60 years (21) | 13 (62) | 8 (38) | 0.032 | 11 (84.6) | 2 (15.4) | 0.500 | ||
 ≥ 60 years (39) | 13 (33.3) | 26 (66.7) |  | 8 (61.5) | 5 (38.5) |  | |||
Sex | Male (54) | 24 (44.4) | 30 (55.6) | 0.472 | 18 (75) | 6 (25) | 0.526 | ||
Female (6) | 2 (33.3) | 4 (66.7) | Â | 2 (100) | 0 | Â | |||
Pattern | Papillary (33) | 15 (45.5) | 18 (54.5) | 0.459 | 4 (26.7) | 11 (64.7) |  < 0.001 | ||
Solid (27) | 11 (40.7) | 16 (59.3) | Â | 11 (100) | 0 | Â | |||
Grade | Low (23) | 17 (74) | 6 (26) |  < 0.001 | 6 (35.3) | 11 (64.7) | 0.002 | ||
High (37) | 9 (24.3) | 28 (75.7) | Â | 9 (100) | 0 | Â | |||
Stage | Superficial (30) | 19 (63.3) | 11 (36.7) | 0.002 | 8 (42) | 11 (58) | 0.01 | ||
Deep (30) | 7 (23.3) | 23 (76.7) | Â | 7 (100) | 0 | Â | |||