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Table 2 Relation between p27 immunoreactivity and clinicopathological variables of the studied cases

From: Assessment of survivin and p27 expression as potential prognostic markers in urothelial cell carcinoma of urinary bladder in Egyptian patients

Item (n.) P27 immunopositivity p-value P27 expression score p-value
Positive n (%) Negative n (%)   Low score n (%) High score n (%)
Mild chronic cystitis (20) 0 12 (100) 0.01 0 0  < 0.001
Urothelial carcinoma (60) 26 (43.3) 34 (56.7)   19 (73) 7 (27)  
Age  < 60 years (21) 13 (62) 8 (38) 0.032 11 (84.6) 2 (15.4) 0.500
 ≥ 60 years (39) 13 (33.3) 26 (66.7)   8 (61.5) 5 (38.5)  
Sex Male (54) 24 (44.4) 30 (55.6) 0.472 18 (75) 6 (25) 0.526
Female (6) 2 (33.3) 4 (66.7)   2 (100) 0  
Pattern Papillary (33) 15 (45.5) 18 (54.5) 0.459 4 (26.7) 11 (64.7)  < 0.001
Solid (27) 11 (40.7) 16 (59.3)   11 (100) 0  
Grade Low (23) 17 (74) 6 (26)  < 0.001 6 (35.3) 11 (64.7) 0.002
High (37) 9 (24.3) 28 (75.7)   9 (100) 0  
Stage Superficial (30) 19 (63.3) 11 (36.7) 0.002 8 (42) 11 (58) 0.01
Deep (30) 7 (23.3) 23 (76.7)   7 (100) 0  
  1. NMIBC Non-muscle invasive bladder cancer, MIBC Muscle-invasive bladder cancer, n Number, % Percentage