Table 1 Relation between survivin immunoreactivity and clinicopathological variables of the studied cases
Item (n) | Survivin immunopositivity | p-value | Survivin expression score | p-value | |||
|---|---|---|---|---|---|---|---|
Positive n (%) | Negative n (%) | Â | Low score n (%) | High score n (%) | |||
Mild chronic cystitis (12) | 0 | 12 (100) |  < 0.001 | 0 | 0 |  < 0.001 | |
Urothelial carcinoma (60) | 36 (60) | 24 (40) | 13 (36) | 23 (64) | |||
Age |  < 60 years (21) | 12 (57) | 9 (43) | 0.476 | 9 (75) | 3 (25) |  < 0.001 |
 ≥ 60 years (39) | 24 (61.5) | 15 (38.5) | 4 (16.7) | 20 (83.3) | |||
Sex | Male (54) | 35 (64.8) | 19 (35.2) | 0.033 | 12 (34.3) | 23 (65.7) | 0.361 |
Female (6) | 1 (16.7) | 5 (83.3) | 1 (100) | 0 | |||
Pattern | Papillary (33) | 11 (33.3) | 22 (66.7) |  < 0.001 | 8 (72.7) | 3 (27.3) | 0.004 |
Solid (27) | 25 (92.6) | 2 (7.4) | 5 (20) | 20 (80) | |||
Grade | Low (23) | 5 (21.7) | 18 (78.3) |  < 0.001 | 3 (60) | 2 (40) | 0.239 |
High (37) | 31 (83.8) | 6 (16.2) | 10 (32.3) | 21 (67.7) | |||
Stage | Superficial (30) | 12 (40) | 18 (60) | 0.002 | 8 (66.7) | 4 (33.3) | 0.01 |
Deep (30) | 24 (80) | 6 (20) | 5 (20.8) | 19 (79.2) | |||