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Table 1 Modified ERAS protocol

From: A preliminary outcome of modified enhanced recovery protocol versus standard of care in radical cystectomy: an Indonesian experience

Item

Component

Preoperative

Stop smoking since deciding to do the surgery

No bowel preparation until planned for colon involvement

Diet: fasting 6 h before surgery (according to anesthesia), carbohydrate loading 4 h before surgery (water with glucose 400 mg)

Prophylactic antibiotic (cephalosporin 2nd or cefazolin)

Consultation with hemato-oncology division for the evaluation of LMWH heparin for the prevention of DVT

Intraoperative

Prevention of hypothermia

Use of multimodal analgesia

Goal directed intraoperative fluid therapy

NGT is removed immediately after surgery

Postoperative

Avoid the use of opioid, instead of using paracetamol and NSAIDS

Postoperative oral intake as early as possible. If tolerance is good, fluid diet can be started 12 h after surgery

Chew gum for 15 min 3 times a day on delayed intake patients

Administration of alinamin F, if needed, to stimulate intestinal motility

If the patient is unable to take diet after 3–4 days, but bowel activity is present, consider diet through NGT. If there is no bowel activity, begin total parenteral nutrition

Postoperative gradual mobilization (since H-0 start to sitting)

Intravenous fluid restriction. Oral fluid intake is more preferred

Giving gastrointestinal prophylaxis with ranitidine until bowel function returns to normal

Administration of anti-emetic, Metoclopramide if needed

  1. ERAS Enhanced Recovery After Surgery, DVT deep venous thrombosis, LMWH Low molecular weight heparin, NGT nasogastric tube, DVT deep venous thrombosis, NSAIDS Non-Steroidal Anti-Inflammatory Drugs, PPI proton pump inhibitors