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Table 6 Effect of aqueous methanolic leaf extract of Triclisia gilletii on plasma biochemistry parameters in animals administered ethane-1,2-diol

From: Effect of moonseed vine (Triclisia gilletii Staner) on ethane-1,2-diol-induced urolithiasis and its renotoxicity in Wistar albino rats

Groups Control Induced I + TGME (50 mg/kg) I + TGME (100 mg/kg) I + TGME (200 mg/kg) I + TH (0.5 µg/kg) TGME (200 mg/kg)
Creatinine (mg/dL) 0.65 ± 0.04**** 0.82 ± 0.01 0.68 ± 0.01** 0.66 ± 0.08** 0.65 ± 0.02*** 0.57 ± 0.07**** 0.59 ± 0.12****
Urea (mg/dL) 30.63 ± 3.74 29.63 ± 4.85 26.08 ± 2.32 28.96 ± 2.86 24.17 ± 2.85 31.64 ± 5.13 30.27 ± 2.80
Uric acid (mg/dL) 0.91 ± 0.18**** 3.27 ± 0.24 2.23 ± 0.13**** 1.76 ± 0.02**** 0.54 ± 0.14**** 2.80 ± 0.30** 0.90 ± 0.06***
Calcium (mg/dL) 10.77 ± 1.56**** 3.44 ± 0.05 6.91 ± 0.40**** 7.87 ± 1.52**** 10.54 ± 0.99**** 10.11 ± 0.21**** 9.91 ± 0.79****
Sodium (mEq/dL) 157.49 ± 9.93**** 116.90 ± 3.8 127.32 ± 5.53 131.15 ± 5.53* 131.98 ± 8.2** 130.18 ± 5.22* 130.36 ± 2.38*
Chloride (mMol/L) 101.32 ± 9.70 92.07 ± 10.98 107.27 ± 10.16 109.19 ± 15.80 95.25 ± 8.86 102.91 ± 13.58 103.79 ± 8.86
Potassium (mEq/L) 6.44 ± 0.63**** 17.62 ± 2.87 2.95 ± 0.58**** 3.50 ± 0.14**** 4.40 ± 0.82**** 3.23 ± 0.48**** 2.95 ± 0.58****
Total Protein (g/L) 59.89 ± 1.91** 53.78 ± 1.02 64.72 ± 2.67**** 59.07 ± 1.21** 61.76 ± 3.33**** 59.03 ± 1.78** 59.59 ± 3.46**
Albumin (g/L) 26.06 ± 1.08** 22.51 ± 1.06 25.34 ± 1.70* 26.38 ± 1.17*** 26.92 ± 1.41*** 26.00 ± 1.56** 26.29 ± 1.91**
Glucose (mg/dL) 174.15 ± 15.02 182.60 ± 15.08 171.04 ± 12.01 170.74 ± 16.00 158.52 ± 13.24 179.15 ± 11.24 155.78 ± 13.24
  1. Data are expressed as mean ± SEM of 6 rats (n = 6); *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001; *denotes that data were compared with ethane-1,2-diol; TGME Triclisia gilletii aqueous methanolic extract, TH tamsulosin hydrochloride