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Table 6 Effect of aqueous methanolic leaf extract of Triclisia gilletii on plasma biochemistry parameters in animals administered ethane-1,2-diol

From: Effect of moonseed vine (Triclisia gilletii Staner) on ethane-1,2-diol-induced urolithiasis and its renotoxicity in Wistar albino rats

Groups

Control

Induced

I + TGME (50 mg/kg)

I + TGME (100 mg/kg)

I + TGME (200 mg/kg)

I + TH (0.5 µg/kg)

TGME (200 mg/kg)

Creatinine (mg/dL)

0.65 ± 0.04****

0.82 ± 0.01

0.68 ± 0.01**

0.66 ± 0.08**

0.65 ± 0.02***

0.57 ± 0.07****

0.59 ± 0.12****

Urea (mg/dL)

30.63 ± 3.74

29.63 ± 4.85

26.08 ± 2.32

28.96 ± 2.86

24.17 ± 2.85

31.64 ± 5.13

30.27 ± 2.80

Uric acid (mg/dL)

0.91 ± 0.18****

3.27 ± 0.24

2.23 ± 0.13****

1.76 ± 0.02****

0.54 ± 0.14****

2.80 ± 0.30**

0.90 ± 0.06***

Calcium (mg/dL)

10.77 ± 1.56****

3.44 ± 0.05

6.91 ± 0.40****

7.87 ± 1.52****

10.54 ± 0.99****

10.11 ± 0.21****

9.91 ± 0.79****

Sodium (mEq/dL)

157.49 ± 9.93****

116.90 ± 3.8

127.32 ± 5.53

131.15 ± 5.53*

131.98 ± 8.2**

130.18 ± 5.22*

130.36 ± 2.38*

Chloride (mMol/L)

101.32 ± 9.70

92.07 ± 10.98

107.27 ± 10.16

109.19 ± 15.80

95.25 ± 8.86

102.91 ± 13.58

103.79 ± 8.86

Potassium (mEq/L)

6.44 ± 0.63****

17.62 ± 2.87

2.95 ± 0.58****

3.50 ± 0.14****

4.40 ± 0.82****

3.23 ± 0.48****

2.95 ± 0.58****

Total Protein (g/L)

59.89 ± 1.91**

53.78 ± 1.02

64.72 ± 2.67****

59.07 ± 1.21**

61.76 ± 3.33****

59.03 ± 1.78**

59.59 ± 3.46**

Albumin (g/L)

26.06 ± 1.08**

22.51 ± 1.06

25.34 ± 1.70*

26.38 ± 1.17***

26.92 ± 1.41***

26.00 ± 1.56**

26.29 ± 1.91**

Glucose (mg/dL)

174.15 ± 15.02

182.60 ± 15.08

171.04 ± 12.01

170.74 ± 16.00

158.52 ± 13.24

179.15 ± 11.24

155.78 ± 13.24

  1. Data are expressed as mean ± SEM of 6 rats (n = 6); *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001; *denotes that data were compared with ethane-1,2-diol; TGME Triclisia gilletii aqueous methanolic extract, TH tamsulosin hydrochloride