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Table 5 Effect of aqueous methanolic leaf extract of Triclisia gilletii on urine biochemistry parameters in animals administered ethane-1,2-diol

From: Effect of moonseed vine (Triclisia gilletii Staner) on ethane-1,2-diol-induced urolithiasis and its renotoxicity in Wistar albino rats

Groups

Control

Induced

I + TGME (50 mg/kg)

I + TGME (100 mg/kg)

I + TGME (200 mg/kg)

I + TH (0.5 µg/kg)

TGME (200 mg/kg)

Creatinine (mg/dL)

109.73 ± 9.34****

57.61 ± 5.03

58.00 ± 8.20

58.98 ± 4.98

85.55 ± 7.67****

99.75 ± 12.37****

72.50 ± 4.2*

Urea (mg/dL)

116.22 ± 14.85****

62.31 ± 1.25

117.55 ± 18.56****

145.40 ± 22.09****

164.25 ± 29.20****

131.22 ± 13.34****

96.70 ± 4.67*

Uric acid (mg/dL)

2.15 ± 0.18

2.27 ± 0.07

2.45 ± 0.04

2.37 ± 0.23

2.45 ± 0.26

2.88 ± 0.09****

2.77 ± 0.04****

Calcium (mg/dL)

5.61 ± 1.81****

9.57 ± 0.13

7.72 ± 0.24*

7.82 ± 0.54*

3.61 ± 0.41****

4.79 ± 0.38****

6.69 ± 1.07****

Sodium (mEq/dL)

34.27 ± 7.20****

53.31 ± 3.45

51.36 ± 5.96

37.46 ± 3.5***

38.925 ± 4.76**

31.82 ± 7.78****

33.89 ± 4.76****

Chloride (mMol/L)

45.47 ± 5.76****

35.95 ± 1.02

85.23 ± 3.50****

60.72 ± 5.35****

59.86 ± 6.51****

90.06 ± 7.89****

40.30 ± 1.23

Potasium (mEq/L)

43.17 ± 5.32****

29.49 ± 4.32

37.79 ± 3.46**

36.98 ± 3.21*

43.83 ± 2.24****

37.24 ± 4.32*

37.26 ± 2.97*

Total Protein (g/L)

6.71 ± 0.56****

12.52 ± 1.2

9.56 ± 1.81**

8.78 ± 0.42***

8.38 ± 1.81****

7.99 ± 1.53****

9.07 ± 0.28***

Albumin (g/L)

1.24 ± 0.47****

2.27 ± 0.15***

1.61 ± 0.18****

0.95 ± 0.06****

1.07 ± 0.12**

1.78 ± 0.18**

1.07 ± 0.16****

Glucose (mg/dL)

4.01 ± 0.90****

8.21 ± 0.77

7.85 ± 0.77

6.20 ± 0.52****

4.74 ± 0.52****

6.75 ± 0.26**

6.93 ± 0.52*

  1. Data are expressed as mean ± SEM of 6 rats (n = 6); *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001; *denotes that data were compared with ethane-1,2-diol; TGME Triclisia gilletii aqueous methanolic extract, TH tamsulosin hydrochloride