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Table 5 Effect of aqueous methanolic leaf extract of Triclisia gilletii on urine biochemistry parameters in animals administered ethane-1,2-diol

From: Effect of moonseed vine (Triclisia gilletii Staner) on ethane-1,2-diol-induced urolithiasis and its renotoxicity in Wistar albino rats

Groups Control Induced I + TGME (50 mg/kg) I + TGME (100 mg/kg) I + TGME (200 mg/kg) I + TH (0.5 µg/kg) TGME (200 mg/kg)
Creatinine (mg/dL) 109.73 ± 9.34**** 57.61 ± 5.03 58.00 ± 8.20 58.98 ± 4.98 85.55 ± 7.67**** 99.75 ± 12.37**** 72.50 ± 4.2*
Urea (mg/dL) 116.22 ± 14.85**** 62.31 ± 1.25 117.55 ± 18.56**** 145.40 ± 22.09**** 164.25 ± 29.20**** 131.22 ± 13.34**** 96.70 ± 4.67*
Uric acid (mg/dL) 2.15 ± 0.18 2.27 ± 0.07 2.45 ± 0.04 2.37 ± 0.23 2.45 ± 0.26 2.88 ± 0.09**** 2.77 ± 0.04****
Calcium (mg/dL) 5.61 ± 1.81**** 9.57 ± 0.13 7.72 ± 0.24* 7.82 ± 0.54* 3.61 ± 0.41**** 4.79 ± 0.38**** 6.69 ± 1.07****
Sodium (mEq/dL) 34.27 ± 7.20**** 53.31 ± 3.45 51.36 ± 5.96 37.46 ± 3.5*** 38.925 ± 4.76** 31.82 ± 7.78**** 33.89 ± 4.76****
Chloride (mMol/L) 45.47 ± 5.76**** 35.95 ± 1.02 85.23 ± 3.50**** 60.72 ± 5.35**** 59.86 ± 6.51**** 90.06 ± 7.89**** 40.30 ± 1.23
Potasium (mEq/L) 43.17 ± 5.32**** 29.49 ± 4.32 37.79 ± 3.46** 36.98 ± 3.21* 43.83 ± 2.24**** 37.24 ± 4.32* 37.26 ± 2.97*
Total Protein (g/L) 6.71 ± 0.56**** 12.52 ± 1.2 9.56 ± 1.81** 8.78 ± 0.42*** 8.38 ± 1.81**** 7.99 ± 1.53**** 9.07 ± 0.28***
Albumin (g/L) 1.24 ± 0.47**** 2.27 ± 0.15*** 1.61 ± 0.18**** 0.95 ± 0.06**** 1.07 ± 0.12** 1.78 ± 0.18** 1.07 ± 0.16****
Glucose (mg/dL) 4.01 ± 0.90**** 8.21 ± 0.77 7.85 ± 0.77 6.20 ± 0.52**** 4.74 ± 0.52**** 6.75 ± 0.26** 6.93 ± 0.52*
  1. Data are expressed as mean ± SEM of 6 rats (n = 6); *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001; *denotes that data were compared with ethane-1,2-diol; TGME Triclisia gilletii aqueous methanolic extract, TH tamsulosin hydrochloride