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Table 2 LD50 determination of aqueous methanolic leaf extract of TGME in orally administered albino rats

From: Effect of moonseed vine (Triclisia gilletii Staner) on ethane-1,2-diol-induced urolithiasis and its renotoxicity in Wistar albino rats

S/N Number of animals TGME (mg/kg) Mortality (x/N) Symptoms
Stage 1 3 0 0/3 Nil
3 10 0/3 Nil
3 100 0/3 Nil
Stage 2 3 1000 0/3 Weakness
3 1600 0/3 Weakness
3 2900 0/3 Weakness
3 5000 0/3 Weakness
  1. LD50 greater than 5000 mg/kg b.w
  2. TGME Triclisia gilletii aqueous methanolic extract