Table 5 List of recent studies and meta-analysis regarding the 14 tag-SNPs investigated
From: Association of single nucleotide polymorphisms with renal cell carcinoma in Algerian population
Cene | 1st Author, Year | Population | Case/Control | SNP | P value |
|---|---|---|---|---|---|
VEGF | |||||
Meta-analyses (8 studies) | Gong M, 2016 | Asian/Caucasian | 1.397/2.094 | rs699947 | * |
262/477 | rs2010963 | NA | |||
677/1.299 | rs833061 | NA | |||
Meta-analyses (14 studies) | Tang J, 2017 | Asian/Caucasian | 1588/2470 | rs699947 | * |
1086/1460 | rs2010963 | * | |||
677/1299 | rs833061 | NA | |||
Meta-analyses (9 studies) | Hou Q, 2017 | Asian/Caucasian | 1588/2470 | rs699947 | * |
2315/3552 | rs2010963 | * | |||
VHL | |||||
Qin C, 2011 | China | 620/632 | rs779805 | NA (0.96) | |
Wang W, 2014 | China | 19/616 | rs779805 | * | |
rs1642742 | * | ||||
Lv C, 2015 | China | 81/80 | rs779805 | * (0.01) | |
EPAS1 | |||||
GWAS | Purdue MP, 2011 | European | 2278/3719 | rs7579899 | * (2.3 × 10−9) |
Cao Q, 2011 | China | 710/760 | NA (0.46) | ||
Su T, 2013 | China | 400/806 | NA (0.43) | ||
Purdue MP, 2014 | African Americans | 255/375 | NA (0.86) | ||
Melkonian SC, 2014 | Texas | 659/699 | * (0.02) | ||
ALDH9A1 | |||||
GWAS | Henrion MYR, 2015 | Western-European | 2.215/8.566 | rs3845536 | * (2.30 × 10−8) |
ATM | |||||
GWAS | Scelo G, 2017 | European | 10.784/20.406 | rs1800057 | * (9.0 × 10−9) |
FAF1 | / | rs4381241 | * (3.1 × 10−10) | ||
LRRIQ4 | / | rs10936602 | * (8.8 × 10−9) | ||
RHOBTB2 | / | rs2241261 | * (5.8 × 10−9) | ||
OBFC1 | / | rs11813268 | * (3.9 × 10−8) | ||
DPF3 | / | rs49030664 | * (2.2 × 10−24) | ||
– | / | rs67311347 | * (2.5 × 10−8) | ||