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Table 5 List of recent studies and meta-analysis regarding the 14 tag-SNPs investigated

From: Association of single nucleotide polymorphisms with renal cell carcinoma in Algerian population

Cene 1st Author, Year Population Case/Control SNP P value
VEGF
Meta-analyses (8 studies) Gong M, 2016 Asian/Caucasian 1.397/2.094 rs699947 *
    262/477 rs2010963 NA
    677/1.299 rs833061 NA
Meta-analyses (14 studies) Tang J, 2017 Asian/Caucasian 1588/2470 rs699947 *
    1086/1460 rs2010963 *
    677/1299 rs833061 NA
Meta-analyses (9 studies) Hou Q, 2017 Asian/Caucasian 1588/2470 rs699947 *
    2315/3552 rs2010963 *
VHL      
  Qin C, 2011 China 620/632 rs779805 NA (0.96)
  Wang W, 2014 China 19/616 rs779805 *
     rs1642742 *
  Lv C, 2015 China 81/80 rs779805 * (0.01)
EPAS1
GWAS Purdue MP, 2011 European 2278/3719 rs7579899 * (2.3 × 10−9)
  Cao Q, 2011 China 710/760   NA (0.46)
  Su T, 2013 China 400/806   NA (0.43)
  Purdue MP, 2014 African Americans 255/375   NA (0.86)
  Melkonian SC, 2014 Texas 659/699   * (0.02)
ALDH9A1
GWAS Henrion MYR, 2015 Western-European 2.215/8.566 rs3845536 * (2.30 × 10−8)
ATM
GWAS Scelo G, 2017 European 10.784/20.406 rs1800057 * (9.0 × 10−9)
FAF1 /    rs4381241 * (3.1 × 10−10)
LRRIQ4 /    rs10936602 * (8.8 × 10−9)
RHOBTB2 /    rs2241261 * (5.8 × 10−9)
OBFC1 /    rs11813268 * (3.9 × 10−8)
DPF3 /    rs49030664 * (2.2 × 10−24)
/    rs67311347 * (2.5 × 10−8)
  1. *Significant association between SNP and RCC, NS: not significant