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Table 3 Association between SNPs rs67311347, ATM rs1800057 and ALDH9A1 rs3845536 and risk of RCC

From: Association of single nucleotide polymorphisms with renal cell carcinoma in Algerian population

Polymorphisms

Cases n %

Controls n %

Pa

OR (95% CI)a

Pa

rs67311347

 GG (ref)

29 (33.33%)

49 (42.98%)

   

 GA

44 (50.57%)

57 (50.00%)

0.08

1.30 (0.71–2.38)

0.44

 AA

14 (16.09%)

8 (7.02%)

 

2.95 (1.10–7.89)

0.03

 G allele (ref)

102 (58.62%)

155 (67.98%)

   

 A allele

72 (41.38%)

73 (32.02%)

 

1.49 (0.99–2.25)

0.05

ATM rs1800057

 CC (ref)

80 (91.95%)

113 (99.00%)

   

 CG

6 (6.90%)

1 (0.88%)

0.03

8.47 (1.00–71.76)

0.04

 GG

1 (1.15%)

0 (0.00%)

 

Inf (Inf–Inf)

0.41

 C allele (ref)

166 (95.40%)

227 (100.00%)

   

 G allele

8 (4.60%)

1 (0.44%)

 

10.93 (1.35–88.31)

0.01

ALDH9A1 rs3845536

 CC (ref)

35 (40.23%)

36 (32.43%)

   

 CT

46 (52.87%)

51 (45.95%)

0.01

0.92 (0.50–1.71)

0.87

 TT

6 (6.90%)

24 (21.62%)

 

0.25 (0.09–0.70

0.007

 C allele

116 (66.67%)

123 (55.41%)

   

 T allele

58 (33.33%)

99 (44.59%)

 

0.62 (0.41–0.93)

0.02

  1. aχ2 test or Fisher’s exact test. OR: Odds Ratio. CI: Confidence Interval