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Table 3 GSTM1, GSTT1 genotypes distribution among tested patients and healthy controls and susceptibility of PCa

From: Association of CYP1A1, GSTM1 and GSTT1 gene polymorphisms with risk of prostate cancer in Algerian population

 

Patients %

Controls %

OR/CI

P value

M+

43 (42.57)

51(50.49)

/

/

M−

58 (57.42)

50 (49.50)

1.37 [0.76–2.4]

0.26

T+

63 (62.37)

78 (77.22)

/

/

T−

38 (37.62)

23 (22.77)

2.03 [1.06–3.99]

0.03

M +/T+

30 (29.70)

41 (40.59)

/

/

M +/T−

13 (12.87)

10 (9.90)

1.76 [0.62–5.2]

0.33

M−/T+

33 (32.67)

37 (36.63)

1.21 [0.60–2.5]

0.61

M−/T−

25 (24.75)

13 (12.87)

2.6 [1.07–6.5]

0.027

  1. GSTM1 positive (M1 +), GSTM1 null (M1 −), GSTT1 positive (T1 +) and GSTT1 null (T1 −)
  2. OR odds ratios, CI confidence intervals. Wild genotypes were used as a reference (GSTM1 positive, GSTT1 positive)