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Table 4 Diagnostic performance of preoperative TRUS and mpMRI for detection of seminal vesicle invasion in the studied 58 patients

From: Feasibility of multi-parametric magnetic resonance imaging in detection and local staging of prostatic carcinoma

Cancer site (number)TRUSmpMRIHistopathology
 Test + veTest − veTest + veTest − ve 
 23505True + ve
 44915253True − ve
Sensitivity (%)40.00 (95% CI 05.27–85.34)100 (95% CI 47.82–100) 
Specificity (%)92.45 (95% CI 81.79–97.91)98.11 (95% CI 89.93–99.95) 
Positive predictive value (%)33.33 (95% CI 04.33–77.72)83.33 (95% CI 35.88–99.58) 
Negative predictive value (%)94.23 (95% CI 84.05–98.79)100 (95% CI 93.15–100) 
Positive likelihood ratio05.30 (95% CI 01.27–22.11)53.00 (95% CI 7.61–369.34) 
Negative likelihood ratio00.65 (95% CI 00.32–01.33)0.00 
AUC00.66 (95% CI 00.53–00.78)0.99 (95% CI 0.92–1.00) 
  1. AUC area under the curve, LHR likelihood ratio, mpMRI multi-parametric magnetic resonance imaging, PV predictive value