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Table 3 Diagnostic performance of preoperative TRUS and mpMRI for detection of extracapsular extension in the studied 58 patients

From: Feasibility of multi-parametric magnetic resonance imaging in detection and local staging of prostatic carcinoma

Cancer site (number)TRUSmpMRIHistopathology
 Test + veTest − veTest + veTest − ve 
 36909True + ve
 84114849True − ve
Sensitivity (%)33.33 (95% CI 07.49–70.07)100 (95% CI 66.37–100) 
Specificity (%)83.67 (95% CI 70.34–92.86)97.96 (95% CI 89.15–99.95) 
Positive predictive value (%)27.27 (95% CI 06.02–60.97)90.00 (95% CI 55.50–99.75) 
Negative predictive value (%)87.23 (95% CI 74.26–95.17)100 (95% CI 92.60–100) 
Positive likelihood ratio02.04 (95% CI 00.67–06.26)49.00 (95% CI 07.04–340.94) 
Negative likelihood ratio00.80 (95% CI 00.49–01.29)0.00 
AUC00.59 (95% CI 00.45–00.71)00.99 (95% CI 00.92–1.00) 
  1. AUC area under the curve, LHR likelihood ratio, mpMRI multi-parametric magnetic resonance imaging, PV predictive value