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Table 2 Diagnostic performance of preoperative TRUS and mpMRI for localization of prostate cancer in the 348 segmental regions in the studied 58 patients

From: Feasibility of multi-parametric magnetic resonance imaging in detection and local staging of prostatic carcinoma

 TRUSmpMRIHistopathology
Cancer site (number)
 Right base404947
 Right mid-zonal314343
 Right apex164
 Left base122727
 Left mid-zonal71818
 Left apex044
 Total89147143
 Test + veTest − veTest + veTest − ve 
 82611421143True + ve
 71985200205True − ve
Sensitivity (%)57.34 (95% CI 48.81–65.57)99.30 (95% CI 96.17–99.98) 
Specificity (%)96.59 (95% CI 93.09–98.62)97.56 (95% CI 94.40–99.20) 
Positive PV (%)92.13 (95% CI 84.46–96.78)96.60 (95% CI 92.24–98.89) 
Negative PV (%)76.45 (95% CI 70.80–81.48)99.50 (95% CI 97.26–99.99) 
Positive LHR16.79 (95% CI 08.00–35.26)40.71 (95% CI 17.13–96.78) 
Negative LHR00.44 (95% CI 00.36–00.54)00.01 (95% CI 00.00–00.05) 
AUC00.77 (95% CI 00.72–00.81)00.98 (95% CI 00.96–00.99) 
  1. AUC area under the curve, LHR likelihood ratio, mpMRI multi-parametric magnetic resonance imaging, PV predictive value